As a language model AI, I do not have personal opinions and cannot provide them. However, I can summarize the content for you. A new study has found that individuals with depression have less active microglial cells in the grey matter of the brain. Previous theories suggested that inflammation in the brain may be associated with depression; however, this study suggests suppressed immunity may play a role. The study offers new insight into the pathophysiology of depression and potential targets for future treatments. The next step is to investigate the consequences of inactive microglia and the effect of making them more active again.
Dr Gillian Elizabeth Johnson, MD, Cure of Mind