butter_trans

Cure of Mind is designed to put your mental wellness first. Discover our global experts and find the support you deserve.

Blogs

Depression Connected to Immune Reaction in Some Persons

Facebook
Twitter
LinkedIn


Summary: Variations in diverse elements of the immune process, both adaptive and innate immune responses, might engage in a job in the development of depression in some people today.

Resource: College of Bristol

A link between depression and improvements in counts of various forms of immune cells in the blood has been uncovered by researchers at the College of Bristol’s MRC Integrative Epidemiology Unit.

These results, posted in Molecular Psychiatry, advise that variations to distinct parts of our immune system—both the innate and adaptive immune response—could enjoy a purpose in creating depression.

Even though quite a few isolated experiments have been performed previously in this place of investigation, this is the to start with large-scale investigation to overview and statistically combine information from all experiments that have noted immune mobile counts, as measured by flow cytometry (a condition-of-the-artwork system for counting immune cells), in adults with and with out a analysis of depression.

By combining these research and growing the complete range of people today involved, more definitive conclusions can be drawn.

The scientists systematically searched two databases and pooled data from 27 published scientific articles that when compared counts of 19 distinctive immune cell styles in older people with and without a depression diagnosis. Each and every study was excellent checked and only superior-excellent research were involved.

Their analyses of 2,277 men and women unveiled that counts of eight diverse varieties of immune cells, e.g., B cells and T cells, had been improved in depression as in contrast to counts viewed in the healthier comparison group with out depression.

These results, posted in Molecular Psychiatry, recommend that improvements to unique components of our immune system—both the innate and adaptive immune response—could enjoy a role in triggering depression. Picture is in the public domain

Éimear Foley, a Ph.D. university student and the study’s direct author at Bristol’s MRC Integrative Epidemiology Device, said, “The question now is no matter whether these improvements in immune cells are a bring about or consequence of depression and we hope to examine this in long term scientific tests.

“It is also crucial to be aware that we are not suggesting that any individual with boosts in these immune mobile styles will create a depressive disorder. Relatively we are highlighting the dissimilarities that may perhaps exist involving people with depression and balanced individuals, that were being involved in our sample, in their counts of specific immune cell kinds.

“Current treatments for depression do not operate for all people and immunotherapy could be valuable for a subgroup of people. Our purpose is to use these conclusions to superior manual our collection of sufferers for long term immunotherapy trials for depression with the hope of doing work to a lot more powerful, individualized care in mental health and fitness.”

About this depression research information

Author: Press Place of work
Resource: College of Bristol
Speak to: Press Workplace – College of Bristol
Graphic: The impression is in the general public area

Initial Analysis: Open up entry.
“Peripheral blood mobile immunophenotype in depression: a systematic evaluation and meta-evaluation” by Éimear M. Foley et al. Molecular Psychiatry

See also

This shows dna

Abstract

Peripheral blood cellular immunophenotype in depression: a systematic critique and meta-analysis

Introduction

Meta-analyses implicate immune dysfunction in depression confirming elevated concentrations of circulating immune proteins (e.g., cytokines) in depression circumstances when compared to controls. White blood cells (WBC) equally produce and are affected by cytokines, and play critical roles in orchestrating innate and adaptive immune responses, but their job in depression stays unclear. As a result, a systematic evaluate of research of various WBC subsets in depression is needed for a greater knowledge of the character of immune dysfunction in this disease.

Strategies

We searched PubMed and PsycINFO databases (inception to 5th April 2022) and conducted a systematic assessment and meta-analysis of determined scientific tests evaluating absolute depend and/or relative proportion of flow cytometry-derived WBC subsets in between depression situations and controls. Picked research have been high quality assessed. Random-effect meta-analysis was carried out.

Results

30-three studies have been bundled and 27 scientific tests (n = 2277) have been meta-analysed. We report an improve in imply absolute counts of WBC (seven studies standardised signify variance [SMD] = 1.07 95% CI, .61–1.53 P < 0.01 I2 = 64%), granulocytes (two studies SMD = 2.07 95% CI, 1.45–2.68 P < 0.01 I2 = 0%), neutrophils (four studies SMD = 0.91 95% CI, 0.23–1.58 P < 0.01 I2 = 82%), monocytes (seven studies SMD = 0.60 95% CI, 0.19–1.01 P < 0.01 I2 = 66%), CD4+ helper T cells (11 studies SMD = 0.30 95% CI, 0.15–0.45 P < 0.01 I2 = 0%), natural killer cells (11 studies SMD = 1.23 95% CI, 0.38–2.08 P < 0.01 I2 = 95%), B cells (10 studies SMD = 0.30 95% CI, 0.03–0.57 P = 0.03 I2 = 56%), and activated T cells (eight studies SMD = 0.45 95% CI, 0.24–0.66 P < 0.01 I2 = 0%) in depression, compared to controls. Fewer experiments reported relative percentage, indicating greater neutrophils and diminished total lymphocytes, Th1, and Th2 cells in depression.

Conclusions

Depression is characterised by common alterations in circulating myeloid and lymphoid cells, regular with dysfunction in both equally innate and adaptive immunity. Immune cells could be handy biomarkers for health issues subtyping and patient stratification in future immunotherapy trials of depression, along with cytokines, other biomarkers, and medical actions.

Facebook
Twitter
LinkedIn

Knowledge is Power

More Updates

Discover our interactive self-help programs

Stay updated

CureClass

Get Started

About

Support

Search

Stay updated

Subscribe now for exclusive insights and updates!

Download the Cure of Mind App

Terms and conditions

These terms and conditions (“Agreement”) set forth the general terms and conditions of your use of the cureofmind.com website (“Website”), “Cure of Mind” mobile application (“Mobile Application”) and any of their related products and services (collectively, “Services”). This Agreement is legally binding between you (“User”, “you” or “your”) and the Private Clinic of Dim. Papadimitriadis & Associates Medical LP: Cure of Mind (“Cure of Mind LP”, “we”, “us” or “our”). If you are entering into this Agreement on behalf of a business or other legal entity, you represent that you have the authority to bind such entity to this Agreement, in which case the terms “User”, “you” or “your” shall refer to such entity. If you do not have such authority, or if you do not agree with the terms of this Agreement, you must not accept this Agreement and may not access and use the Services. By accessing and using the Services, you acknowledge that you have read, understood, and agree to be bound by the terms of this Agreement. You acknowledge that this Agreement is a contract between you and Cure of Mind LP, even though it is electronic and is not physically signed by you, and it governs your use of the Services.

Table of contents

  1. Accounts and membership
  2. User content
  3. Billing and payments
  4. Accuracy of information
  5. Third party services
  6. Backups
  7. Links to other resources
  8. Confidentiality and Privacy
  9. Professional Liability
  10. Refund Policy
  11. Prohibited uses
  12. Intellectual property rights
  13. Disclaimer of warranty
  14. Limitation of liability
  15. Indemnification
  16. Severability
  17. Dispute resolution
  18. Assignment
  19. Changes and amendments
  20. Acceptance of these terms
  21. Contacting us


Accounts and membership

You must be at least 16 years of age to use the Services. By using the Services and by agreeing to this Agreement you warrant and represent that you are at least 16 years of age.

If you create an account on the Services, you are responsible for maintaining the security of your account and you are fully responsible for all activities that occur under the account and any other actions taken in connection with it. We may, but have no obligation to, monitor and review new accounts before you may sign in and start using the Services. Providing false contact information of any kind may result in the termination of your account. You must immediately notify us of any unauthorized uses of your account or any other breaches of security. We will not be liable for any acts or omissions by you, including any damages of any kind incurred as a result of such acts or omissions. We may suspend, disable, or delete your account (or any part thereof) if we determine that you have violated any provision of this Agreement or that your conduct or content would tend to damage our reputation and goodwill. If we delete your account for the foregoing reasons, you may not re-register for our Services. We may block your email address and Internet protocol address to prevent further registration.

User content

We do not own any data, information or material (collectively, “Content”) that you submit on the Services in the course of using the Service. You shall have sole responsibility for the accuracy, quality, integrity, legality, reliability, appropriateness, and intellectual property ownership or right to use of all submitted Content. We may monitor and review the Content on the Services submitted or created using our Services by you. You grant us permission to access, copy, distribute, store, transmit, reformat, display and perform the Content of your user account solely as required for the purpose of providing the Services to you. Without limiting any of those representations or warranties, we have the right, though not the obligation, to, in our own sole discretion, refuse or remove any Content that, in our reasonable opinion, violates any of our policies or is in any way harmful or objectionable. You also grant us the license to use, reproduce, adapt, modify, publish or distribute the Content created by you or stored in your user account for commercial, marketing or any similar purpose.

Billing and payments

You shall pay all fees or charges to your account in accordance with the fees, charges, and billing terms in effect at the time a fee or charge is due and payable. If auto-renewal is enabled for the Services you have subscribed for, you will be charged automatically in accordance with the term you selected. If, in our judgment, your purchase constitutes a high-risk transaction, we will require you to provide us with a copy of your valid government-issued photo identification, and possibly a copy of a recent bank statement for the credit or debit card used for the purchase. We reserve the right to change products and product pricing at any time. We also reserve the right to refuse any order you place with us. We may, in our sole discretion, limit or cancel quantities purchased per person, per household or per order. These restrictions may include orders placed by or under the same customer account, the same credit card, and/or orders that use the same billing and/or shipping address. In the event that we make a change to or cancel an order, we may attempt to notify you by contacting the e-mail and/or billing address/phone number provided at the time the order was made.

Accuracy of information

Occasionally there may be information on the Services that contains typographical errors, inaccuracies or omissions that may relate to product descriptions, promotions and offers. We reserve the right to correct any errors, inaccuracies or omissions, and to change or update information or cancel orders if any information on the Services or Services is inaccurate at any time without prior notice (including after you have submitted your order). We undertake no obligation to update, amend or clarify information on the Services including, without limitation, pricing information, except as required by law. No specified update or refresh date applied on the Services should be taken to indicate that all information on the Services or Services has been modified or updated.

Third party services

If you decide to enable, access or use third party services, be advised that your access and use of such other services are governed solely by the terms and conditions of such other services, and we do not endorse, are not responsible or liable for, and make no representations as to any aspect of such other services, including, without limitation, their content or the manner in which they handle data (including your data) or any interaction between you and the provider of such other services. You irrevocably waive any claim against Cure of Mind LP with respect to such other services. Cure of Mind LP is not liable for any damage or loss caused or alleged to be caused by or in connection with your enablement, access or use of any such other services, or your reliance on the privacy practices, data security processes or other policies of such other services. You may be required to register for or log into such other services on their respective platforms. By enabling any other services, you are expressly permitting Cure of Mind LP to disclose your data as necessary to facilitate the use or enablement of such other service.

Backups

We perform regular backups of the Website and its Content and will do our best to ensure completeness and accuracy of these backups. In the event of the hardware failure or data loss we will restore backups automatically to minimize the impact and downtime.

Although the Services may link to other resources (such as websites, mobile applications, etc.), we are not, directly or indirectly, implying any approval, association, sponsorship, endorsement, or affiliation with any linked resource, unless specifically stated herein. We are not responsible for examining or evaluating, and we do not warrant the offerings of, any businesses or individuals or the content of their resources. We do not assume any responsibility or liability for the actions, products, services, and content of any other third parties. You should carefully review the legal statements and other conditions of use of any resource which you access through a link on the Services. Your linking to any other off-site resources is at your own risk.

Confidentiality and Privacy

Clause: Confidentiality and Privacy Agreement

By using the online psychotherapy platform “Cure of Mind,” the client acknowledges and agrees to maintain strict confidentiality and privacy regarding all information shared during the therapy sessions. This includes any personal, medical, or sensitive data disclosed to the therapist (psychologist or medical doctor or nutritionist) during the course of treatment.

“Cure of Mind” commits to safeguarding the client’s personal information and adheres to all applicable laws and regulations pertaining to data protection and privacy. The client’s data will be securely stored and accessible only to authorized personnel involved in the therapy process.

The client agrees not to record, share, or distribute any part of the therapy sessions, including audio, video, or written content, without explicit written consent from both “Cure of Mind” and the therapist (psychologist or medical doctor or nutritionist).

In the event of any legal obligation to disclose confidential information, “Cure of Mind” will make reasonable efforts to notify the client beforehand, except in cases where immediate disclosure is required by law or poses a risk to the client’s safety or the safety of others.

“Cure of Mind” encourages open and honest communication during therapy sessions; however, the client is responsible for ensuring their online environment is private and free from potential eavesdropping or unauthorized access during sessions.

The client understands that while “Cure of Mind” takes all necessary precautions to maintain confidentiality, the use of online platforms carries inherent risks related to data transmission, and “Cure of Mind” cannot guarantee absolute security. Therefore, the client assumes responsibility for any risks associated with sharing information through the online platform.

By proceeding with therapy sessions on “Cure of Mind,” the client acknowledges and accepts the terms of this confidentiality and privacy agreement, providing their informed consent to engage in therapy under these conditions.

Professional Liability

“Cure of Mind” is a platform that connects clients with selected licensed psychologists, medical doctors, and nutritionists who provide professional psychotherapy, nutritional and medical services. The liability for the provision of these services lies solely with the individual professionals conducting the therapy sessions.

All therapists, medical doctors, and nutritionists associated with “Cure of Mind” are independent practitioners, responsible for their own actions and conduct during therapy sessions. “Cure of Mind” does not directly oversee or monitor the content or conduct of individual therapy sessions due to privacy reasons. As such, “Cure of Mind” cannot be held liable for any professional misconduct, malpractice, or ethical violations that may occur during therapy sessions.

Clients engaging in therapy sessions through “Cure of Mind” understand that the psychologists, medical doctors, and nutritionists are bound by their respective professional codes of ethics, licensing regulations, and applicable laws governing their practice. Clients are encouraged to discuss any concerns or issues with their respective psychologist, medical doctor, or nutritionist directly.

In the event of any disputes or concerns related to the services provided by the psychologists, medical doctors, or nutritionists, clients agree to address such matters directly with the professional practitioner involved. “Cure of Mind” will not mediate or be held liable for any disputes between clients and professionals arising from therapy sessions conducted through the platform.

“Cure of Mind” may provide general guidelines and policies to promote a safe and positive therapeutic environment, but clients acknowledge that the final responsibility for adherence to ethical and professional standards lies with the individual professionals providing the services.

By using the “Cure of Mind” platform and engaging in sessions with the licensed psychologists, medical doctors, and nutritionists, clients implicitly acknowledge and accept that “Cure of Mind” cannot be held responsible for any professional liability or misconduct that may arise during the course of therapy sessions. Clients agree to release “Cure of Mind” from any claims or damages related to the professional conduct of the therapists, medical doctors, and nutritionists providing services on the platform.

Refund Policy

Since we offer non-tangible, irrevocable goods we do not provide refunds after the service or product is purchased, which you acknowledge prior to purchasing. Please make sure that you’ve carefully read the service description before making a purchase.

Prohibited uses

In addition to other terms as set forth in the Agreement, you are prohibited from using the Services or Content: (a) for any unlawful purpose; (b) to solicit others to perform or participate in any unlawful acts; (c) to violate any international, federal, provincial or state regulations, rules, laws, or local ordinances; (d) to infringe upon or violate our intellectual property rights or the intellectual property rights of others; (e) to harass, abuse, insult, harm, defame, slander, disparage, intimidate, or discriminate based on gender, sexual orientation, religion, ethnicity, race, age, national origin, or disability; (f) to submit false or misleading information; (g) to upload or transmit viruses or any other type of malicious code that will or may be used in any way that will affect the functionality or operation of the Services, third party products and services, or the Internet; (h) to spam, phish, pharm, pretext, spider, crawl, or scrape; (i) for any obscene or immoral purpose; or (j) to interfere with or circumvent the security features of the Services, third party products and services, or the Internet. We reserve the right to terminate your use of the Services for violating any of the prohibited uses.

Intellectual property rights

“Intellectual Property Rights” means all present and future rights conferred by statute, common law or equity in or in relation to any copyright and related rights, trademarks, designs, patents, inventions, goodwill and the right to sue for passing off, rights to inventions, rights to use, and all other intellectual property rights, in each case whether registered or unregistered and including all applications and rights to apply for and be granted, rights to claim priority from, such rights and all similar or equivalent rights or forms of protection and any other results of intellectual activity which subsist or will subsist now or in the future in any part of the world. This Agreement does not transfer to you any intellectual property owned by Cure of Mind LP or third parties, and all rights, titles, and interests in and to such property will remain (as between the parties) solely with Cure of Mind LP. All trademarks, service marks, graphics and logos used in connection with the Services, are trademarks or registered trademarks of Cure of Mind LP or its licensors. Other trademarks, service marks, graphics and logos used in connection with the Services may be the trademarks of other third parties. Your use of the Services grants you no right or license to reproduce or otherwise use any of Cure of Mind LP or third party trademarks.

Disclaimer of warranty

You agree that such Service is provided on an “as is” and “as available” basis and that your use of the Services is solely at your own risk. We expressly disclaim all warranties of any kind, whether express or implied, including but not limited to the implied warranties of merchantability, fitness for a particular purpose and non-infringement. We make no warranty that the Services will meet your requirements, or that the Service will be uninterrupted, timely, secure, or error-free; nor do we make any warranty as to the results that may be obtained from the use of the Service or as to the accuracy or reliability of any information obtained through the Service or that defects in the Service will be corrected. You understand and agree that any material and/or data downloaded or otherwise obtained through the use of Service is done at your own discretion and risk and that you will be solely responsible for any damage or loss of data that results from the download of such material and/or data. We make no warranty regarding any goods or services purchased or obtained through the Service or any transactions entered into through the Service unless stated otherwise. No advice or information, whether oral or written, obtained by you from us or through the Service shall create any warranty not expressly made herein.

Limitation of liability

To the fullest extent permitted by applicable law, in no event will Cure of Mind LP, its affiliates, directors, officers, employees, agents, suppliers or licensors be liable to any person for any indirect, incidental, special, punitive, cover or consequential damages (including, without limitation, damages for lost profits, revenue, sales, goodwill, use of content, impact on business, business interruption, loss of anticipated savings, loss of business opportunity) however caused, under any theory of liability, including, without limitation, contract, tort, warranty, breach of statutory duty, negligence or otherwise, even if the liable party has been advised as to the possibility of such damages or could have foreseen such damages. To the maximum extent permitted by applicable law, the aggregate liability of Cure of Mind LP and its affiliates, officers, employees, agents, suppliers and licensors relating to the services will be limited to an amount no greater than one dollar or any amounts actually paid in cash by you to Cure of Mind LP for the prior one month period prior to the first event or occurrence giving rise to such liability. The limitations and exclusions also apply if this remedy does not fully compensate you for any losses or fails of its essential purpose.

Indemnification

You agree to indemnify and hold Cure of Mind LP and its affiliates, directors, officers, employees, agents, suppliers and licensors harmless from and against any liabilities, losses, damages or costs, including reasonable attorneys’ fees, incurred in connection with or arising from any third party allegations, claims, actions, disputes, or demands asserted against any of them as a result of or relating to your Content, your use of the Services or any willful misconduct on your part.

Severability

All rights and restrictions contained in this Agreement may be exercised and shall be applicable and binding only to the extent that they do not violate any applicable laws and are intended to be limited to the extent necessary so that they will not render this Agreement illegal, invalid or unenforceable. If any provision or portion of any provision of this Agreement shall be held to be illegal, invalid or unenforceable by a court of competent jurisdiction, it is the intention of the parties that the remaining provisions or portions thereof shall constitute their agreement with respect to the subject matter hereof, and all such remaining provisions or portions thereof shall remain in full force and effect.

Dispute resolution

The formation, interpretation, and performance of this Agreement and any disputes arising out of it shall be governed by the substantive and procedural laws of Greece without regard to its rules on conflicts or choice of law and, to the extent applicable, the laws of Greece. The exclusive jurisdiction and venue for actions related to the subject matter hereof shall be the courts located in Greece, and you hereby submit to the personal jurisdiction of such courts. You hereby waive any right to a jury trial in any proceeding arising out of or related to this Agreement. The United Nations Convention on Contracts for the International Sale of Goods does not apply to this Agreement.

Assignment

You may not assign, resell, sub-license or otherwise transfer or delegate any of your rights or obligations hereunder, in whole or in part, without our prior written consent, which consent shall be at our own sole discretion and without obligation; any such assignment or transfer shall be null and void. We are free to assign any of its rights or obligations hereunder, in whole or in part, to any third party as part of the sale of all or substantially all of its assets or stock or as part of a merger.

Changes and amendments

We reserve the right to modify this Agreement or its terms related to the Services at any time at our discretion. When we do, we will revise the updated date at the bottom of this page, post a notification within the Services. We may also provide notice to you in other ways at our discretion, such as through the contact information you have provided.

An updated version of this Agreement will be effective immediately upon the posting of the revised Agreement unless otherwise specified. Your continued use of the Services after the effective date of the revised Agreement (or such other act specified at that time) will constitute your consent to those changes.

Acceptance of these terms

You acknowledge that you have read this Agreement and agree to all its terms and conditions. By accessing and using the Services you agree to be bound by this Agreement. If you do not agree to abide by the terms of this Agreement, you are not authorized to access or use the Services.

Contacting us

If you have any questions, concerns, or complaints regarding this Agreement, we encourage you to contact us using the details below:

cureofmind.com/support

This document was last updated on August 27, 2023

Download the Cure of Mind App

Informed Consent for Psychotherapy, Nutritional or Medical Counselling

Introduction:

The purpose of this form is to provide you with information about psychotherapy, nutritional counseling, and medical counseling and to obtain your consent to participate in these treatments. These services involve professional relationships between you and your therapist, nutritionist, and medical doctor to address your emotional, nutritional, and medical needs. This form is intended to give you information that will help you make an informed decision about whether or not to engage in these treatments.

Therapist Qualifications:

Your therapist is a licensed mental health professional who has completed an advanced degree in psychology or a related field and has been trained to provide psychotherapy. Your nutritionist and medical doctor are also licensed professionals with expertise in their respective fields. They are committed to providing you with the highest quality of care possible.

Goals and Objectives:

The goals of psychotherapy are to help you overcome emotional or psychological difficulties that are causing distress in your life. Nutritional counseling aims to support your dietary needs, promote healthy eating habits, and address specific nutritional concerns. Medical counseling focuses on providing you with medical guidance, treatment options, and managing your overall health.

Treatment Methods:

Your therapist will use a variety of treatment methods in psychotherapy, including talk therapy, cognitive-behavioral therapy, psychodynamic therapy, mindfulness techniques, or other approaches. Your nutritionist will provide nutritional education, create personalized meal plans, and offer guidance on making healthy food choices. Your medical doctor will assess your medical history, perform necessary examinations, refer you for lab tests and recommend appropriate medical treatments.

Risks and Benefits:

Psychotherapy, nutritional counseling, and medical counseling can be beneficial in various ways, such as improving your emotional well-being, enhancing your nutrition, and promoting better physical health. However, there are also some risks associated with these treatments. Risks may include experiencing uncomfortable emotions during therapy, potential changes in your relationships, and the possibility of addressing challenging nutritional or medical issues.

Confidentiality:

Your therapist, nutritionist, and medical doctor are committed to protecting your privacy and will keep all information discussed during your sessions confidential, with some exceptions. These exceptions include situations where there is an imminent risk of harm to yourself or others, or where there is a legal obligation to disclose information.

Duration and Frequency of Sessions:

The length and frequency of therapy sessions, nutritional counseling sessions, and medical counseling appointments will depend on your individual needs and goals. Typically, therapy and counseling sessions are scheduled weekly or biweekly and last for approximately 50 minutes. While nutritional counselling appointments last up 45 minutes and medical counseling appointments last up to 30 minutes and their frequency may vary.

Fees and Payment:

Fees are charged on a session-by-session or appointment basis and may be covered by insurance if this is available to you.

For insurance coverage, it is important you understand your insurance policy and coverage. You should forward your detailed invoice from Cure of Mind to your insurance provider and discuss with them whether the services provided by the therapist, nutritionist, and medical doctor are eligible for coverage as per the terms of your insurance plan. 

Consent:

By ticking the box “Informed Consent” on the booking form, you acknowledge that you have read and understand the information provided and that you have had the opportunity to read the information about psychotherapy, nutritional counseling, and medical counseling provided on Cure of Mind and to ask questions in our Help Center, or during your first appointment with one of our professionals. You consent to participate in these treatments and understand that you may withdraw your consent at any time.

We respect your privacy

You can change your preferences at any time by clicking on the “Cookie Settings” link at the bottom of this site.

ACCEPT ALL
REFUSE ALL